WebmasterWorld has a great article on how to maximize your revenue with adsense using smart pricing. The author gives you his top four ways to do just that. For more read the entire article.
(1) Collect relevant information including EPC data, AdWords PPCs, and identify which pages are using SmartPricing the most.
(2) Improve your EPC – lots of ways to do this.
(3) Watch and monitor your results over next several days
(4) Remove the ads from the low paying pages and direct them (some how) to the higher paying pages.